ABSTRACT
Objective To study the clinical effect of laser therapy for patients with diabetic retinopathy of different stages,and to observe the prognosis,thus to provide basis for clinical diagnosis and treatment.Methods 103 patients(197 eyes) with diabetic retinopathy were selected,they were divided into group A(69 eyes with proliferative diabetic retinopathy) and group B(45 eyes of non proliferative diabetic retinopathy) and group C(83 eyes with severe non proliferative diabetic retinopathy).All patients were treated with laser therapy,compared the improvement of visual acuity and retinal lesion of 12-18 months in each group and the final number of surgical cases needed.Results Visual acuity improvement:the total effective rate of group A was 69.6％ (48/69),which of group B was 91.1％ (41/45),which of group C was 78.3％ (65/83),the differences were statistically significant (x2 =14.216,12.132,8.316,all P ＜ 0.05).Improvement of retinopathy:the total effective rate of group A was 76.8％ (53/69),that of group B was 95.5％ (43/45),which of group C was 85.5％ (71/83),the differences were statistically significant (x2 =12.031,8.042,8.129,all P ＜0.05).9 cases needed surgical treatment in group A,accounting for 13.0％,1 case needed surgical treatment in group B,accounting for 2.2％,3 cases needed surgical treatment in group C,accounting for 3.6％,which of group A was significantly higher than group B (x2 =8.021,P ＜0.05) and group C (x2 =7.103,P ＜ 0.05),there was no statistically significant difference between group B and group C (x2 =0.632,P ＞ 0.05).Conclusion Laser treatment of different stages of diabetic retinopathy patients has different effects,choosing the right time to use laser therapy has great significance for improving the visual acuity and fundus diseases of the patients.
ABSTRACT
Objective To explore the prevalence and risk factors of retinopathy ( ROP) in premature infants and full term infants.Methods 563 premature infants and full term infants in Weihai Hospital Affiliated to Medical College of Qingdao University from January 2014 to January 2015 were selected,and the clinical data were retrospec-tively analyzed.Results 61 children with ROP,the incidence rate of ROP was 10.83%.Men incidence rate of ROP (10.68%) and female incidence of ROP (11.02%) showed no significant difference (χ2 =1.045,P>0.05).The gestational age >35 weeks, 31 -34 weeks,≤30 weeks neonatal ROP incidence rates were 1.53%, 15.04%, 35.71%,the difference between groups was statistically significant(χ2 =11.455,P2 000g,1 500g-2 000g,0.05).Multivariate unconditional logistic regression analysis,the independent risk fac-tors of retinal diseases for preterm and full-term children small for gestational age children were birth gestational age,birth weight,mechanical ventilation,apnea.Conclusion The age of birth,birth weight,mechanical ventilation and apnea are the risk factors of ROP.It should be attached great importance to the clinical treatment to prevent the development of the disease and improve the prognosis of patients.
ABSTRACT
Objective To explore the intrauterine disorders that leads to infertility and sterility in women.Methods From March 1993 to March 2008,a total of 2077 patients with infertility received hysteroscopic examination at Nanjing Drum Tower Hospital.Among the patients,531 were diagnosed with intrauterine abnormalities including primary infertility in 172(32.4%) cases,secondary infertility in 315 cases(59.3%),and sterility in 44(8.3%).The clinical data of these patients were analyzed retrospectively.Results The most common cause of infertility and sterility in the patients was intrauterine adhesion(231 cases,43.5%),followed by uterine deformities(152,28.6%) and endometrial polyps(88,16.6%).In the primary infertility group,the most common reason was endometrial polyps,which was detected in 38.4% of the cases(66/172).The rate was significantly higher than that in the secondary infertility group(6.0%,19/315) and sterility group(6.8%,3/44)(?2=80.7630,P=0.000;?2=16.0463,P=0.000).While in the secondary infertility group,intrauterine adhesion was detected in most of the patients(60.6%,191/315),that was significantly more than that in the sterility and primary groups(25.0%,11/44,?2=19.9232,P=0.000 and 16.9%,29/172,?2=86.0747,P=0.000,respectively).For the patients with sterility,the disease was caused by uterine deformities mostly(65.9%,29/44),which is significantly different from the other two groups(secondary group:25.1%,79/315,?2=30.5994,P=0.000;primary group:25.6%,44/172,?2=25.4673,P=0.000).Conclusion The major causes of primary infertility,secondary infertility,and sterility are endometrial polyp,intrauterine adhesion,and uterine deformities respectively.